Sunday, September 14, 2025

B. pharmacy TU Pharmacotherapeutics old question paper/ 2081/2082




 

Medicine to Delay Periods – How to Take? Side Effects


Hello, with festivals approaching, one of the common concerns for many women is their period. Even when planning a long journey, periods often become a worry. Many wish if periods could be postponed for a while. There are certain medicines that can delay periods, but they should not be used unless absolutely necessary.

✓ First, for women already using contraceptive pills: if you finish 21 days of pills and instead of taking the usual 7-day break you directly start the next month’s pack, then your period will be delayed.

✓ Second, for women not using contraceptive pills: there is a medicine called Norethisterone. In Nepal, it is available under different brand names such as Femitrone, Norgest, Feminine, Primount, Noreth, etc.


How does it work?
Norethisterone tablets work like the natural hormone progesterone in women. As long as you continue taking the medicine, your period will be stopped. You need to take one tablet three times a day, starting at least three days before your expected period. It should not be taken for more than 17 days. While on the medicine, periods will be delayed, and once you stop taking it, your period usually comes within three days.





What does this tablet do?
Norethisterone is a synthetic form of the hormone progesterone. It prevents the lining of the uterus (endometrium) from breaking down. Normally, when this lining sheds, bleeding (period) starts. The tablets usually come in 5 mg doses, taken three times daily to postpone periods.


How long can it be taken?
It can be taken for up to 17 days at most. It should not be taken longer than this because side effects may increase, and it can disturb the body’s hormonal balance.


How to take the medicine?
Take a 5 mg Norethisterone tablet three times a day, always at the same time.


Possible side effects
Since it is only used for a short time, major side effects are uncommon. However, some women may experience nausea, dizziness, headache, irregular periods later, or breast tenderness.


Does it prevent pregnancy?
No, this medicine does not prevent pregnancy.


What if the period does not start even after stopping the medicine?
Normally, periods occur within 2–3 days after stopping the medicine, sometimes it may take 3–4 days longer. If periods do not occur, a pregnancy test should be done.


Who should not take this medicine?

  • Anyone allergic to the medicine

  • Pregnant women

  • Women with blood clotting problems

  • Those with deep vein thrombosis (DVT)

  • Those with heart disease or history of heart attack

  • Women with liver problems

  • Women who had jaundice during pregnancy

Wednesday, September 3, 2025

🌿 How to Get Rid of Dandruff: Home Remedies & Best Medicated Anti-Dandruff Shampoos

 Dandruff is a common issue that most people experience. Some have dandruff only during winter, while others face it in both winter and summer. It often causes intense itching and discomfort, making people eager to find a solution.

Today, I will be discussing how to get rid of dandruff.

Dandruff is not a severe medical condition, but for young people, it can be embarrassing to have visible flakes in their hair. It causes itchiness and results in white flakes appearing on the scalp.


Causes of Dandruff

Dandruff can occur due to various reasons, including:

  • Oily scalp: People with excessive oil production on their scalp are more prone to dandruff.
  • Fungal infection: A type of fungus called Malassezia can infect the scalp, leading to dandruff.
  • Skin conditions: Issues like psoriasis, eczema, or contact dermatitis can cause dandruff.
  • Hair products: Some hair products can trigger dandruff in certain individuals.
  • Poor hygiene: Not washing hair regularly or maintaining poor personal hygiene is one of the most common causes.

Home Remedies for Dandruff

There are several home remedies as well as medicated shampoos for treating dandruff. My recommendation is to try home remedies first, and if they do not work, you can opt for medicated treatments.

1. Maintain Proper Hygiene

  • Use a good anti-dandruff shampoo and wash your hair every other day.
  • If you have an oily scalp, you need to take extra care and wash your hair more frequently.

2. Aloe Vera (Ghieu Kumari)

  • Apply aloe vera gel to your scalp 2-3 hours before washing your hair.
  • Consistent use every time you wash your hair can help eliminate dandruff.

3. Coconut Oil

  • Avoid using other oils when you have dandruff.
  • However, applying 4-5 teaspoons of coconut oil to your scalp one hour before washing can help reduce dandruff.
  • Studies suggest that coconut oil has antibacterial and antifungal properties.

4. Apple Cider Vinegar, Baking Soda, and Lemon Water

  • Applying any of these to the scalp for a few minutes before washing can help reduce dandruff.
  • However, these remedies may cause hair fall if used excessively.

Medicated Shampoos for Dandruff

If home remedies do not work, you can use medicated shampoos to treat dandruff. The most effective shampoos contain antifungal properties that help eliminate dandruff.

Common Medicated Shampoos

  • Ketoconazole shampoo (most widely used)
  • Salicylic acid-based shampoo
  • Pyrithione zinc shampoo
  • Coal tar shampoo
  • Selenium sulfide shampoo

These shampoos are readily available at pharmacies. Among them, Ketoconazole shampoo is the most commonly used.

How to Use Ketoconazole Shampoo?

  1. Wet your hair with water.
  2. Apply the shampoo to the scalp and massage gently.
  3. Leave it on for 10 minutes before rinsing.
  • If you have an oily scalp, wash your hair daily and use Ketoconazole shampoo twice a week.
  • If your hair is dry or frizzy, using Ketoconazole shampoo once a week is sufficient.
  • Apply the medicated shampoo only to the scalp and use your regular shampoo for the rest of your hair.
  • Stop using Ketoconazole shampoo once your dandruff disappears (after 2-4 weeks).

How to Prevent Dandruff?

  • Eat a balanced diet rich in vitamins and nutrients.
  • Maintain scalp hygiene by washing your hair regularly.
  • Allow your hair to dry in natural sunlight after washing.
  • Avoid excessive use of hair styling products containing chemicals.

By following these simple steps, you can effectively prevent and treat dandruff.

Let me know if you need any modifications or further improvements! 😊

Monday, September 1, 2025

How to Take Abortion Pills? What is Medical Abortion?

 Many women take abortion pills at home without proper guidance, which has even resulted in loss of lives. To prevent such risks and to save women’s lives, I have tried to provide some advice and information regarding this medicine.


What is Medical Abortion?

✓ Medical abortion means terminating a pregnancy by taking medicines.
✓ In medical abortion, surgery is not required. It can be done at home under the supervision of a trained health worker.
✓ This method is safe within the first 10 weeks of pregnancy (or within 70 days from the last menstrual period).
However, it is very important to get detailed information before proceeding with this process.


Information About the Medicines

  1. 1 tablet 💊 Mifepristone 200 mg

  2. 4 tablets 💊💊💊💊 Misoprostol 200 mcg each (total 800 mcg)

  • Mifepristone blocks the effect of the hormone progesterone, which is necessary for pregnancy.

  • Misoprostol causes the uterus to contract, leading to abortion.




Method of Taking the Medicines

  1. First, swallow Mifepristone with water.

  2. After taking Mifepristone, wait for 24–48 hours.

  3. Then take Misoprostol:

    • Place 4 tablets either under the tongue (sublingual) or 2 on the right cheek and 2 on the left cheek (buccal).

    • Keep them for 30 minutes without swallowing.

    • After 30 minutes, swallow the remaining medicine with water.


What Happens After Taking the Medicines?

  • After taking Mifepristone, some women may start bleeding, while others may not notice any changes.

  • After Misoprostol (24–48 hours later), bleeding should occur.

  • Abdominal pain, cramping, nausea, and vomiting are common.

  • Bleeding may be heavier than a normal period. Each woman experiences bleeding and abdominal pain differently.


What to Do if Side Effects Occur?

✓ If nausea/vomiting occurs → take antiemetics like Ondansetron
✓ If abdominal pain occurs → take painkillers like Brufen (Ibuprofen)
✓ If there is heavy bleeding → use sanitary pads
✓ On the day of taking Misoprostol, side effects like nausea, headache, fever, or diarrhea may occur.
✓ If side effects do not improve within 1 day → visit the nearest health facility.


When to Be Extra Careful?

✓ If there is excessive bleeding (soaking 2 sanitary pads within 1 hour, for 2 hours continuously)
✓ If dizziness, extreme tiredness, or weakness occurs
✓ If there is severe abdominal pain or foul-smelling vaginal discharge
✓ If high fever occurs
✓ If feeling extremely unwell or persistent vomiting

Visit doctor or hospital


How to Know if the Medicine Worked?

✓ If bleeding and abdominal cramps occur after taking the medicine → the abortion has worked.
✓ If no bleeding occurs, or only very light bleeding continues even after 4–5 days → the medicine has not worked, and you may still be pregnant.


When Can Sexual Intercourse Resume?

After taking the medicines, sexual activity can be resumed only once all side effects are gone and the body has recovered.


How to Prevent Future Unwanted Pregnancies?

  • Repeated abortions can cause serious health problems.

  • Therefore, it is important to use contraceptive methods like birth control pills, injections, condoms, or permanent methods to prevent future unwanted pregnancies.