Monday, October 21, 2019

पैंतालिसौं दीक्षान्त समारोहको आवेदन गर्ने म्याद थप सम्बन्धी सूचना |

त्रिभुवन विश्वविद्यालय
परीक्षा नियन्त्रण कार्यालय, बल्खु 
पैंतालिसौं दीक्षान्त समारोहको आवेदन गर्ने म्याद थप सम्बन्धी सूचना 
 
त्रिभुवन विश्वविद्यालयको पैंतालिसौं दीक्षान्त समारोहमा आवेदन भर्ने विद्यार्थीहरुको लागि इलष्लिभ फारम भर्ने म्याद २०७६ साल कार्तिक ८ गतेसम्म थप गरिएकोले सरोकारवाला सम्बन्धित सबैलाई जानकारी गराईन्छ ।  

पुनश्च :

मिति २०७५ साल जेष्ठ मसान्तसम्ममा ट्रान्स्त्रृmप्ट लिईसकेका सम्पूर्ण विद्यार्थीहरुले २०७७ मंसिर मसान्तसम्ममा मूल प्रमाणपत्र (Original Certificate) लिईसक्नु पर्नेछ । अन्यथा सो अवधि पछि अतिरिक्त शुल्क लाग्ने व्यहोरा समेत सूचित गरिन्छ । 

नि.परीक्षा नियन्त्रक
 
To till the form click in the link below. 

Wednesday, October 16, 2019

Menstrual cycle



The cyclical event  seen in sexually mature female in which there is per vaginal bleeding due to sheding of endometrium because of withdrawl of estrogen and progestrogen

The average menstrual cycle lasts 28 days

Menstrual stage
The first 3 to 5 days of the cycle are characterized by menstrual flow.
There is withdrawal of  hormones due to degeneration of  hormones so constriction of  endometrial arteriole then tissue ischemia and shedding of endometrium which leads to pervaginal bleeding

Proliferative (estrogenic) stage
. Begins during the later stages of menstrual flow and continues through the 13th or
14th day
Ovarian events
There is follicular growth due to stimulation of  FSH . The growing follicle produce estrogen which leads to endometrial change in uterus
Uterine events
Due to action of estrogen there is massive hyperplasia of endometrial cells
Hyperplasia of glands and watery secrection
Endometrium become highly vascularise

As the estrogen level persistently become high it gives positive feedback to hypothalamus which leads to massive release of  LH that leads to release of ovum from the ovary called as ovulation after ovulation graffian follicle changed into corpus leuteum which secrects progesterone and the cycle moves to secrectory phase

Secretory phase
Corpus leutem secrects progesteron which leads to fowling endometrial changes
·        Continues the hypertrophy of the endometrium
·        There is increased vascularity and increased edema.
·        Hypertrophy of  the gland and thick secrection from endometrium
·        Blood vessels become more spiral.
      


     Some remedies for painful mensuration:
  1. Hot water therapy
  2. Warm bath
  3. Light exercise 
  4. Balanced diet
  5. Some NSAIDS like Mefenamic acid, Ibuprofen etc.










Friday, October 11, 2019

What is needed to be a Pharmacist ?

To become a well established pharmacist is not a easy job. I am not talking about assistant pharmacy or pharmacy assistant. In this article i am talking about either bachelor degree in Pharmacy, Pharm.D or Master in Pharmacy.

- First you have to determine yourself to be a good pharmacist before starting a course.
- Then you have to choose a college which you like the most and have the well resources throughout your course, please don't choose   college due to accommodation facilities instead choose college according to qualified teaching technique or facilities.
- After choosing the college look all the syllabus and plan accordingly.
- Study harder for exam, if you get failed then please donot loose hope  since it is the subject where more than 60% student passed in re-exam.
- Focus on Practical too.
- Choose which field you want to go after the course.
- Pass the license exam.
- Work in the sector you interested in the most.
- Don't feel frustrating while working.

After certain time of your working you will reach in your destination. you will either
- Pharmaceutical Company Manager
- Hospital Pharmacist
- Clinical Pharmacist
- Professor
- Researcher

But in some country you have to do post graduation as per your interested field like Industrial pharmacy, Clinical Pharmacy, Pharmacology etc.

It is the field not to loose hope, keep patience and keep going. You will reach in the destination as per your actual potential.  

Thursday, October 10, 2019

Pharmacovigilance

Definition:

According to WHO Pharmacovigilance (PV) is defined as the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem.

Status of Pharmacovigillance in Nepal

GoN nominated Department of Drug Administration (DDA) in October 2004 as the focal point (National Pharmacovigilance centre) to liaison with WHO collaborating centre for International Drug Monitoring, Sweden and started collecting adverse drug reactions. Nepal became a WHO programme member in July 2006.

At present, there are 12 regional pharmacovigilance centers in Nepal

  • Tribhuvan University Teaching Hospital, Maharajgunj
  • Civil Service Hospital, Minbhawan
  • Manipal Teaching Hospital, Pokhara
  • KIST Medical College, Imadol
  • Nepal Medical College Teaching Hospital, Jorpati
  • Patan Hospital, Lalitpur
  • B.P Koirala Institute of Health Science (BPKIHS), Dharan
  • Dhulikhel Hospital, Banepa
  • Shree Birendra Hospital, Chhauni
  • Norvic International Hospital, Thapathali
  • Nepal Cancer Hospital and Research Center, Harisiddhi
  • College of Medical Sciences - Teaching Hospital

These regional pharmacovigilance centers operate under DDA (DDA being the National centre for ADR monitoring). The regional centers reports ADRs to the National center (DDA) via ‘Vigiflow’ (an online program) which are then forwarded to the Uppsala Monitoring Center (UMC) by the National Centre. The National database contains about 547 ADR reports so far.

Tuesday, October 8, 2019

औसधिको उचित प्रयोगमा फार्मासिस्ट को आवस्यकता


अलि सम्पन्न मुलुकमा डाक्टरले औसधिको पुर्जा लेखिसकेपछि फार्मासिस्टले प्रमाडित गर्ने गर्छन अनि नर्सेले प्रमारि करण  हेरिसकेपछि बल्ल बिरामीलाई औसधि लगाइदिने गर्दछन। तर हाम्रो नेपालमा येस्तो गर्ने चलन अझै सम्भब नै हुन सकिरहेको छैन, जसका कारण देशमा उत्पन्न भएका क्लिनिकल फार्मासिस्टहरु बिदेसिनु बाहेक अरु केहि विकल्प नै रहेन।  नेपालमा औसधि पसले वाहेक फार्मासिस्ट औसधिको उचित प्रयोग गर्न जानेको एक बीज्ञ  पनि हो भन्ने सोच अझै पनि नेपाली समाजमा विकसित हुन सकिरहेको छैन।  

अत: अझै भन्नु पर्दा कतिपय औसधि हुन्छन जुन बिरामीलाई लगाइदिसकेपछि  तेस्को निरन्तररुपमा सरीरमा केहि toxic  effect देखाउछ कि भनेर जचिरहनु पर्दछ, जुन कुरा फार्मासिस्टले वाहेक अरु ले गर्दैन। औसधिको उचित प्रयोग नहुदा बिरामीको ज्यान  पनि जान सक्छ. तर हामीले रोगले बिरामीको ज्यान गयो कि औसधिको अनुचित प्रयोग ले हामीलाइ  अवागत नै हुदैन।

क्लिनिकल फार्मासिस्टले गर्ने कामहरु-

- औसधि सहि मात्रामा दिए नदिएको जाच गर्ने
- औसधिले adverse reaction गर्छ  कि जाच गर्ने
- औसधिको उचित प्रयोगको लागि अन्य स्वास्थ्यकर्मीलाइ सल्ला सुझाब दिने 
- antibiotic को उचित प्रयोग गर्नका लागि उत्साहान गर्ने
- बिरामीलाई औसधिले केहि नकारात्मक असर गर्यो कि भनेर जाच गर्ने
- लिवर खराब अनि किड्नी खराब भएका  व्याक्तिलाइ डोज पत्ता लगाउने 

देशका दक्ष्य जनसक्ति विदेश मा पलाएन हुनु पर्ने अनि देशका नागरिक औसधिको  अनुचित प्रयोग ले ज्यान गुमाउन  पर्ने अवास्था छ ,अब नेपाल सरकार को  यो कुराको  गम्बिर  ध्यानाकर्सन हुन जरुरि छ।  



Tuesday, October 1, 2019

Dengue Fever- symptoms, prevention and treatment in Nepal

Dengue fever is going viral nowadays in Nepal basically in Rupandehi dristricts. It is caused by the single bite of infected mosquito infected by dengue virus. It is characterized by dengue kits test and also low platelets counts.

Sign and Symptoms
- High fever upto  104 degree F.
- Headache
- Joints and muscle pain
-Nausea and vomiting
- Anorexia
- Pain of eyelids

Prevention
- Clean the environment, where there high prone of mosquito.
- Use mosquito repellents while sleeping.
Were full cloth while going out.

Treatment
Since this is the viral infection so there are no any specific medicine unless treating its symptoms.
- Paracetamol 500 mg three times a day to control fever.
- antiemetic like domperidone to control nausea and vomiting.
- Oral Re hydration Solution to compensate fluid loss.

Home remedy and foods supplements
- Pomegranate
- Soup
- Apple
- Plenty of water
- Green vegetables
- Liquid containing food
- Coconut water

Since there is no any medicine for dengue virus, unless dangerous symptoms arises like bleeding from nose, mouth, stool and urine, there in no need to hospitalization. if Platelets count falls to the minimum hospitalization is required. 'It takes upto 7 to 14 days to complete recovery.